Principal Clinical Scientist

**Principal Clinical Scientist (AI Training)** **About The Role** What if your expertise in clinical trial design and regulatory science could directly shape how AI reasons about medical evidence for researchers and clinicians worldwide? We're looking for a Principal Clinical Scientist to bring senior\-level clinical rigor to cutting\-edge AI development. You'll work with leading AI research teams to ensure that the clinical data powering next\-generation AI systems meets the same standards expected in real\-world regulatory submissions. This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work on their own terms. * Organization: Alignerr * Type: Hourly Contract * Location: Remote * Commitment: 10–40 hours/week **What You'll Do** * Design and review clinical trial protocols used to generate high\-quality, regulator\-ready datasets for AI training * Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance * Evaluate AI\-generated clinical analyses for scientific soundness and alignment with regulatory expectations * Identify gaps in how AI models reason about clinical outcomes and provide expert corrective feedback * Help establish quality standards for clinical data used across AI research workflows * Work independently and asynchronously — fully on your own schedule **Who You Are** * Senior\-level clinical scientist with hands\-on experience designing protocols for regulatory submission * Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodies * Strong grounding in clinical research methodology, biostatistics, or translational science * Naturally rigorous — you hold clinical data to the highest standards of accuracy and consistency * Clear communicator who can translate complex clinical concepts into structured, actionable feedback **Nice to Have** * Prior experience with data annotation, data quality review, or AI evaluation workflows * Background in pharmacovigilance, medical affairs, or clinical operations * Familiarity with AI tools or machine learning systems in a biomedical context * Experience contributing to cross\-functional or distributed research teams **Why Join Us** * Work directly on frontier AI systems shaping the future of clinical and biomedical research * Fully remote and flexible — work when and where it suits you * Freelance autonomy with the structure of meaningful, expert\-level work * Influence how AI understands, evaluates, and communicates real\-world clinical evidence * Collaborate with leading AI research labs and scientists from around the world * Potential for ongoing work and contract extension as new projects launch